A subpopulation of t(2;14)(p11;q32) cells in ataxia telangiectasia B lymphocytes |
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| Authors: | S V Butterworth A M R Taylor |
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| Institution: | (1) Cancer Research Campaign Laboratories, Department of Cancer Studies, Medical School, University of Birmingham, B15 2TJ Birmingham, UK |
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| Abstract: | Summary Partially purified B cells from ataxia telangiectasia (A-T) patients and normal individuals were stimulated with Staphylococcus aureus Cowan I organisms (SAC). High levels of apparently random rearrangements were seen in the A-T B cells only. In addition a t(2;14)(p11;q32) rearrangement was identified in B cells from more than one patient. |
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