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Computer simulations of pacemaker shift in the sinoatrial node |
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| Authors: | Syunyaev R. A. Aliev R. R. |
| Affiliation: | 1.Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia ;2.Moscow Institute of Physics and Technology, Dolgoprudnyi, Moscow Region, 141700, Russia ; |
| Abstract: | The initiation and propagation of electrical pulses in the sinoatrial node under normal conditions and after application of acetylcholine have been simulated. It has been found that normally a single or a few leading centers are formed in the tissue. When acetylcholine is applied, a temporary functional block of conduction may appear; the leading center migrates under these conditions. |
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