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Primary pleural synovial sarcoma with diffuse pleural involvement: A case report |
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| Institution: | 1. Oxford University Hospitals NHS Foundation Trust, Oxford, UK;2. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford, UK;1. Department of Pharmacology, SRM College of Pharmacy, SRM Institute of science and technology, Chennai, Tamil Nadu, India;2. Department of General Medicine, E.S.I. Hospital, Medavakkam Tank Road, 600023 Ayanavaram Chennai, Tamil Nadu, India;3. Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels Institute of Science Technology and Advanced Studies (VISTAS), 600117 Pallavaram, Chennai, India |
| Abstract: | Synovial sarcoma (SS) is a mesenchymal tumor which generally affects the soft tissues of the extremities. Primary pleural synovial sarcoma (PPSS) is a very rare and aggressive subtype of SS. A 73-year-old male patient presented with chest-back pain and dyspnea. Hypermetabolic diffuse pleural lesions were detected in 18F-FDG PET/CT performed after pleural nodular thickenings were observed on CT. As the result of the molecular analysis performed in the excisional biopsy, SYT-SSX mutation was detected and the patient was diagnosed as SS. Pazopanib treatment was commenced. We are reporting a very rare case of PPSS with diffuse pleural involvement. |
| Keywords: | Synovial sarcoma Pleura PET/CT Sarcome synovial Plèvre TEP/TDM |
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