Deep learning for protein complex structure prediction |
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Institution: | Science for Life Laboratory, 172 21 Solna, Sweden;Department of Biochemistry and Biophysics, Stockholm University, 106 91 Stockholm, Sweden |
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Abstract: | Recent developments in the structure prediction of protein complexes have resulted in accuracies rivalling experimental methods in many cases. The high accuracy is mainly observed in dimeric complexes and other problems such as protein disorder and predicting the structure of host-pathogen interactions remain. This review highlights the foundation for current accurate structure prediction of protein complexes and possible ways to address the remaining limitations. |
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