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Benzopyran sulfonamides as KV1.5 potassium channel blockers
Authors:Lloyd John  Atwal Karnail S  Finlay Heather J  Nyman Michael  Huynh Tram  Bhandaru Rao  Kover Alexander  Schmidt Joan  Vaccaro Wayne  Conder Mary Lee  Jenkins-West Tonya  Levesque Paul
Affiliation:Bristol-Myers Squibb Pharmaceutical Research Institute, PO Box 5400, Princeton, NJ 08543-5400, USA. john.lloyd@bms.com
Abstract:K(V)1.5 blockers have the potential to be atrium-selective agents for treatment of atrial fibrillation. The benzopyrans provide a template for the synthesis of potent and selective K(V)1.5 blockers.
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