Anxiolytic effect of dehydroepiandrosterone sulfate in male mice with high anxiety level |
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| Authors: | Ovsiukova M V Amikishieva A V Kudriavtseva N N Obut T A |
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| Affiliation: | Institute of Physiology, Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences, Novosibirsk. |
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| Abstract: | Effects of dehydroepiandrosterone sulfate (DHEAS, 30 mg/kg, i.p., 4 and 28 hours after an injection) on CBA/Lac male mice with increased level of anxiety resulting from chronic (20-day) social confrontations were studied in two behavioral tests. The anxiolytic effect of DHEAS was observed both 4 and 28 hours after an injection in the partition test of social interactions and in the plus-maze test. |
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