The growing importance of fat in regenerative medicine |
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Authors: | Strem Brian M Hedrick Marc H |
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Institution: | Macropore Biosurgery Inc., 6740 Top Gun Street, San Diego, California 92121, USA. bstrem@macropore.com |
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Abstract: | A recent publication by Michael Longaker and colleagues represents a landmark for the use of adipose tissue as a source of cells for tissue regeneration. The authors investigated the ability of adipose tissue-derived cells (ADCs) to regenerate critical size calvarial (superior portion of the skull) defects in mice by using a novel osteoconducive apatite-coated Poly-lactic-co-glycolic acid (PLGA) scaffold for cell delivery. Direct comparison of this osteogenic ability was performed with bone marrow stromal cells and juvenile calvarial-derived osteoblasts. |
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