Structural genomics: opportunities and challenges |
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Authors: | Mittl P R Grütter M G |
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Institution: | Institute of Biochemistry, University of Zürich, Winterthurerstrasse 190, 8057 Zürich, Switzerland. |
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Abstract: | Following the complete genome sequencing of an increasing number of organisms, structural biology is engaging in a systematic approach of high-throughput structure determination called structural genomics to create a complete inventory of protein folds/structures that will help predict functions for all proteins. First results show that structural genomics will be highly effective in finding functional annotations for proteins of unknown function. |
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