|
|||||
|
|
A Dynamic Model of HIV Integrase Inhibition and Drug Resistance |
|
| Authors: | Alex L. Perryman Garrett M. Morris Yuhui Cheng Kevin Whitby Chris Phillips |
| Affiliation: | 1 Department of Molecular Biology, The Scripps Research Institute, MB5, 10550 N Torrey Pines Road, La Jolla, CA 92037, USA 2 Discovery Chemistry, Pfizer Global Research and Development, Ramsgate Road, Sandwich, Kent CT13 9NJ, UK 3 Department of Chemistry and Biochemistry and the Howard Hughes Medical Institute, University of California, San Diego, 9500 Gilman Drive, # 0365, La Jolla, CA 92093-0365, USA 4 Anti-Virals Research Unit, Pfizer Global Research and Development, Ramsgate Road, Sandwich, Kent CT13 9NJ, UK |
| Abstract: | |
| Keywords: | HIV-1, human immunodeficiency virus type 1 CA, cytosine-adenosine MD, molecular dynamics SAR, structure-activity relationship EqMD, equilibration MD QM, quantum mechanical G.M., Gasteiger-Marsili |
| 本文献已被 ScienceDirect 等数据库收录！ | |