Nisin-controlled production of pediocin PA-1 and colicin V in nisin- and non-nisin-producing Lactococcus lactis strains |
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| Authors: | Horn Nikki Fernández Antonio Dodd Helen M Gasson Michael J Rodríguez Juan M |
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| Affiliation: | Food Safety Science Division, BBSRC Institute of Food Research, Norwich Research Park, Colney, Norwich, UK. |
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| Abstract: | The introduction of chimeric genes encoding the fusion leader of lactococcin A-propediocin PA-1 or procolicin V under the control of the inducible nisA promoter and the lactococcin A-dedicated secretion genes (lcnCD) into Lactococcus lactis strains, including a nisin producer, expressing the two component regulator NisRK led to the production or pediocin PA-1 or colicin V, respectively. |
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