Chromosomal fragmentation is the major consequence of the rdgB defect in Escherichia coli |
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Authors: | Lukas Lisa Kuzminov Andrei |
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Affiliation: | Department of Microbiology, University of Illinois, Urbana, Illinois 61801, USA. |
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Abstract: | The rdgB mutants depend on recombinational repair of double-strand breaks. To assess other consequences of rdgB inactivation in Escherichia coli, we isolated RdgB-dependent mutants. All transposon inserts making cells dependent on RdgB inactivate genes of double-strand break repair, indicating that chromosomal fragmentation is the major consequence of RdgB inactivation. |
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