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Preparation of thianucleoside derivatives. |
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| Authors: | J Uenishi M Motoyama K Takahashi |
| Affiliation: | Department of Chemistry, Okayama University of Science, Japan. |
| Abstract: | 1'-Deoxy-4'-thioribonucleoside 1 was synthesized from acyclic allylic alcohol 2 by 8 steps. TMSOTf and SnCl4 were found to be a good mediator for the key coupling of thiafuranose part with pyrimidine base to give beta-isomer preferentially. |
| Keywords: | |