Expression of the murine interferon gamma receptor in Xenopus laevis oocytes |
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Authors: | C S Kumar T M Mariano M Noe A K Deshpande P M Rose S Pestka |
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Institution: | Department of Molecular Genetics and Microbiology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, Piscataway 08854. |
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Abstract: | This study describes the isolation of mRNA for the murine interferon gamma receptor and its expression in frog oocytes. The binding properties and apparent molecular weight of the murine interferon gamma receptor protein synthesized in frog oocytes is similar to that found on mouse cells. This is the first report of a functional receptor for a polypeptide ligand (interferon gamma) expressed in and directly assayed on frog oocytes. |
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