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| 自由基稳衡性动态 | |
| 引用本文： | Fang YZ,Yang S,Wu G. 自由基稳衡性动态[J]. 生理科学进展, 2004, 35(3): 199-204 |
| 作者姓名： | Fang YZ Yang S Wu G |
| 作者单位： | 1. 北京放射医学研究所生物化学与分子生物学研究室,北京,100850 2. 中国农业大学畜牧系动物营养研究室,北京,100094 3. 美国得克萨斯州立农工大学畜牧系,得州,77843 |
| 摘 要： | 虽然自由基具有很活泼的化学性质 ,但在需氧生物的进化中却一直保持着自由基稳衡性动态的特征 ,体现于某些生物程序 ,包括 :在生理情况下履行其生理作用 ;维持其产生与清除于接近平衡 ;余剩的自由基引发生物大分子的损伤及其损伤可被修复。营养素及其代谢物和“必需”抗氧化剂对自由基稳衡态的正常维持起着关键性作用。谷胱甘肽及其它生物物质的稳衡性动态与自由基稳衡性动态有着协调的相互关系。在各种生活条件下 ,不同年龄的健康人体内自由基稳衡性动态应维持良好 ,以预防衰老前氧化应激与氧化损伤的发生 |
| 关 键 词： | 自由基 自由基稳衡性动态 营养素 抗氧化剂 谷胱甘肽 |
Free radical homeostasis |
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| Fang Yun-Zhong,Yang Sheng,Wu Guoyao. Free radical homeostasis[J]. Progress in Physiological Sciences, 2004, 35(3): 199-204 | |
| Authors: | Fang Yun-Zhong Yang Sheng Wu Guoyao |
| Affiliation: | Department of Biochemistry and Molecular Biology, Beijing Institute of Radiation Medicine, Beijing 100850. |
| Abstract: | Although free radicals have reactive chemical properties, the characteristics of free radical homeostasis have been maintained during the evolution of oxygen-requiring organisms. These characteristics are implicated in performing diverse physiological functions and none of deleterious effects resulting from neat balance of production and scavenging of free radicals, as well as the repair of radical-induced damage of bio-macromolecules under physiological conditions. Nutrients and their metabolites along with"essential" antioxidants play crucial roles in maintaining free radical homeostasis. Glutathione homeostasis interrelates synergistically with free radical homeostasis. Free radical homeostasis should be maintained well in healthy humans at different ages and under various living conditions in order that oxidative stress and its induced oxidative damage will be prevented or ameliorated before aging. |
| Keywords: | Free radical Free radical homeostasis Nutrient Antioxidant Glutathione |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ | |