The Role of Multiphosphorylated Peptides in Mineralized Tissue Regeneration |
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| Authors: | Keith J. Cross N. Laila Huq Neil M. O’Brien-Simpson John W. Perich Troy J. Attard Eric C. Reynolds |
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| Affiliation: | (1) Cooperative Research Centre for Oral Health Science, School of Dental Science, Bio21 Institute, The University of Melbourne, 720 Swanston Street, Victoria, 3010, Australia |
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| Abstract: | Several multiple phosphoseryl-containing proteins have been identified in mineralising tissue and body fluids where they have been proposed to act as nucleators and/or regulators of biomineralisation. In particular, the unique features of the multiphosphorylated caseins from milk and phosphophoryn from dentine enable them to have a role in mineralised tissue regeneration. In this review, three examples of therapeutic applications using multiphosphorylated peptides are described. |
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| Keywords: | Phosphopeptides Mineralisation Biomimetic |
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