The metabolism of cycloartenol,lanosterol, 24-methylenecholesterol and fucosterol in Chlorella ellipsoidea |
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Authors: | Larry B Tsai Glnn W Patterson |
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Institution: | Department of Botany, University of Maryland, College Park, MD 20742, U.S.A. |
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Abstract: | Lanosterol and cycloartenol labelled with tritium at C-2, and 24-methylenecholesterol and fucosterol labelled with tritium at C-2 and C-4 were fed to actively growing cultures of Chlorella ellipsoidea. Lanosterol and cycloartenol were converted to each of the five desmethyl sterols of C. ellipsoidea. Lanosterol was more efficiently incorporated than cycloartenol.Although there was some evidence for the reduction of the 24-methylene group, it was apparent that 24-methylene-cholesterol was converted primarily to the C29 sterols, clionasterol and poriferasterol. Labelled fucosterol was reduced at the 24(28) double bond, producing clionasterol. |
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Keywords: | Chlorophyceae lanosterol cycloartenol 24-methylenecholesterol fucosterol sterol biosynthesis |
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