Equilibrium states and oscillations for localized two-enzyme kinetics: A model for circadian rhythms |
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Authors: | Howard D. Thames Allen D. Elster |
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Affiliation: | Department of Biomathematics, M. D. Anderson Hospital and Tumor Institute Houston, Texas 77025, U.S.A. |
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Abstract: | Two models of localized catalysis are presented. In Problem I we study cooperatively coupled enzymes bound to membranes separated from each other. In Problem II the interaction of a membrane bound with a soluble (homogeneously distributed on a finite interval) enzyme is considered, with non-linearity in the bulk solution. One of the models is developed to describe cellular circadian rhythms at the molecular level. |
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Keywords: | Circadian Rhythms Oscillations Bistability Membranes |
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