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Equilibrium states and oscillations for localized two-enzyme kinetics: A model for circadian rhythms
Authors:Howard D. Thames  Allen D. Elster
Affiliation:Department of Biomathematics, M. D. Anderson Hospital and Tumor Institute Houston, Texas 77025, U.S.A.
Abstract:Two models of localized catalysis are presented. In Problem I we study cooperatively coupled enzymes bound to membranes separated from each other. In Problem II the interaction of a membrane bound with a soluble (homogeneously distributed on a finite interval) enzyme is considered, with non-linearity in the bulk solution. One of the models is developed to describe cellular circadian rhythms at the molecular level.
Keywords:Circadian Rhythms  Oscillations  Bistability  Membranes
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