Compensatory testosterone secretion in unilaterally orchidectomized rats |
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| Authors: | S. Lindgren J-E. Damber H. Carstensen |
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| Affiliation: | Department of Physiology, University of Umeå, S-901 87 Umeå, Sweden |
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| Abstract: | Blood and testis samples were taken from rats 3 weeks after unilateral (sinistral) orchidectomy or sham operation to study the regulation of circulating testosterone. Although plasma testosterone concentrations did not differ, the concentration of testicular testosterone was twofold greater in orchidectomized rats than in sham operated controls. At autopsy, weights of right testes as well as Leydig cell number of orchidectomized and control rats were similar. These observations indicate that, after unilateral orchidectomy, compensatory hypersecretion is not related to compensatory testicular hypertrophy. |
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