|
|||||
|
|
Biased exonization of transposed elements in duplicated genes: A lesson from the TIF-IA gene |
|
| Authors: | Maayan Amit Noa Sela Hadas Keren Ze'ev Melamed Inna Muler Noam Shomron Shai Izraeli Gil Ast |
| Institution: | (1) Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, 69978, Israel;(2) Chaim Sheba Cancer Research Center, Tel Hashomer, Israel;(3) Pediatric Hemato-Oncology, Sheba Medical Center, Tel Hashomer, Israel;(4) Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA |
| Abstract: | BackgroundGene duplication and exonization of intronic transposed elements are two mechanisms that enhance genomic diversity. We examined whether there is less selection against exonization of transposed elements in duplicated genes than in single-copy genes. |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ | |