Research of the origin of a particular Tunisian group using a physical marker and Alu insertion polymorphisms |
| |
Authors: | El Moncer Wifak Bahri Raoudha Esteban Esther Abdenni-Guenounou Bouthaina Moral Pedro Ben Chibani Jemni Chaabani Hassen |
| |
Institution: | Laboratory of Human Genetics and Anthropology, Faculty of Pharmacy, University of Monastir, Monastir, Tunisia. |
| |
Abstract: | The aim of this study was to show how, in some particular circumstances, a physical marker can be used along with molecular markers in the research of an ancient people movement. A set of five Alu insertions was analysed in 42 subjects from a particular Tunisian group (El Hamma) that has, unlike most of the Tunisian population, a very dark skin, similar to that of sub-Saharans, and in 114 Tunisian subjects (Gabes sample) from the same governorate, but outside the group. Our results showed that the El Hamma group is genetically midway between sub-Saharan populations and North Africans, whereas the Gabes sample is clustered among North Africans. In addition, The A25 Alu insertion, considered characteristic to sub-Saharan Africans, was present in the El Hamma group at a relatively high frequency. This frequency was similar to that found in sub-Saharans from Nigeria, but significantly different from those found in the Gabes sample and in other North African populations. Our molecular results, consistent with the skin color status, suggest a sub-Saharan origin of this particular Tunisian group. |
| |
Keywords: | Tunisian population El Hamma group skin color Alu insertion polymorphisms people movement history |
本文献已被 PubMed 等数据库收录! |
|