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Phenylbutazone and Flunixin Meglumine Fail to Show Beneficial Effects on Bovine Subclinical Mastitis |
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| Authors: | Pyörälä Satu Pätilä Jaana Sandholm Markus |
| Affiliation: | 131.Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Helsinki, Finland ;231.Ambulatory Clinic, College of Veterinary Medicine, SF-04840, Hautjarvi, Finland ; |
| Abstract: | Inflammation is caused by the release of chemical mediators from tissues and migra-tory cells. These mediators include leuco-trienes and prostaglandins (PGs), which are generated from arachidonic acid (Vane & Botting 1987). Elevated concentrations of arachidonic acid metabolites have been found in experimental and spontaneous ma-stitis, which indicates that these substances may have a role in the pathophysiologic process of mastitis (Anderson et al. 1985, Atroshietal 1986). |
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