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Dietary fatty acid intake affects the risk of developing bone marrow lesions in healthy middle-aged adults without clinical knee osteoarthritis: a prospective cohort study |
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| Authors: | Yuanyuan Wang Miranda L Davies-Tuck Anita E Wluka Andrew Forbes Dallas R English Graham G Giles Richard O'Sullivan Flavia M Cicuttini |
| Institution: | (1) Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Alfred Hospital, Commercial Road, 3004 Melbourne, VIC, Australia;(2) Baker Heart and Diabetes Research Institute, Commercial Road, 3004 Melbourne, VIC, Australia;(3) Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, University of Melbourne, Swanston Street, 3053 Carlton, VIC, Australia;(4) Cancer Epidemiology Centre, The Cancer Council Victoria, Rathdowne Street, 3053 Carlton, VIC, Australia;(5) MRI Unit, Symbion Imaging, Epworth Hospital, Bridge Road, 3121 Richmond, VIC, Australia |
| Abstract: | IntroductionFatty acids have been implicated in osteoarthritis (OA), yet the mechanism by which fatty acids affect knee structure and consequently the risk of knee OA has not been fully elucidated. Higher intakes of fatty acids have been shown to be associated with the risk of bone marrow lesions (BMLs) in a healthy population. The aim of this study was to examine the association between fatty acid consumption and the incidence of BMLs in healthy middle-aged adults without clinical knee OA. |
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