Thiopyronine and 8-methoxypsoralen sensitized photodynamic effect on DNA synthesis in yeast |
| |
| Authors: | E -R Lochmann R Roth |
| |
| Institution: | (1) Institut für Biochemie und Molekularbiologie, Freie Universität Berlin, Ehrenbergstrasse 26-28, D-1000 Berlin 33, Germany;(2) Department of Biology, Illinois Institute of Technology, 60616 Chicago, IL, USA |
| |
| Abstract: | Summary The synthesis of DNA in growing yeast cells was investigated after photodynamic treatment of the cells with thiopyronine (TP) and visible light or with 8-methoxypsoralen (8-MOP) and UVA light.DNA synthesis was inhibited after photodynamic treatment with 8-MOP but not after photodynamic treatment with TP. This result is further evidence that the photodynamic effect with TP does not attack nuclear DNA in eucaryotic cells. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
