Reconsolidation: the advantage of being refocused |
| |
Authors: | Dudai Yadin |
| |
Affiliation: | Department of Neurobiology, The Weizmann Institute of Science, Rehovot 76100, Israel. yadin.dudai@weizmann.ac.il |
| |
Abstract: | Ample evidence suggests that upon their retrieval, items in long-term memory enter a transient special state, in which they might become prone to change. The process that generates this state is dubbed 'reconsolidation'. The dominant conceptual framework in this revitalized field of memory research focuses on whether reconsolidation resembles consolidation, which is the process that converts an unstable short-term memory trace into a more stable long-term trace. However, this emphasis on the comparison of reconsolidation to consolidation deserves reassessment. Instead, the phenomenon of reconsolidation, irrespective of its relevance to consolidation, provides a unique opportunity to tap into the molecular, cellular and circuit correlates of memory persistence and retrieval, of which we currently know only little. |
| |
Keywords: | |
本文献已被 ScienceDirect PubMed 等数据库收录! |
|