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Molecular architecture of zinc chelating small molecules that inhibit spliceosome assembly at an early stage
Authors:Vishal Patil  Josh C Canzoneri  Timur R Samatov  Reinhard Lührmann  Adegboyega K Oyelere
Institution:1.School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332-0400, USA;2.Department of Cellular Biochemistry, Max Planck Institute for Biophysical Chemistry, D-37077 Göttingen, Germany;3.Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia 30332-0400, USA
Abstract:
Keywords:pre-mRNA splicing  spliceosome assembly  inhibitors  zinc chelator
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