Chromosomal assignment of the gene for the ubiquinone-binding protein of human mitochondrial cytochrome bc1 complex |
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| Authors: | Y Hosokawa H Suzuki M Nishikimi A Matsukage M C Yoshida T Ozawa |
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| Affiliation: | Department of Biomedical Chemistry, Faculty of Medicine, University of Nagoya, Japan. |
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| Abstract: | The ubiquinone-binding protein (QP-C) is a nuclear-encoded subunit of the cytochrome bc1 complex in the mitochondrial respiratory chain and is thought to be involved in the electron transfer reaction coupled to energy transduction. We recently isolated a nuclear gene for human QP-C and used, in the present study, its fragment as a probe for Southern blot analysis of EcoRI-digested DNAs prepared from 14 human-mouse somatic cell hybrids. The results indicated that the human QP-C gene is located on chromosome 8. |
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