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Crystallization of the Lys49 PLA2 homologue, myotoxin II, from the venom of Atropoides nummifer
Authors:Watanabe Leandra  Gava Lisandra M  Angulo Yamileth  Lomonte Bruno  Arni Raghuvir K
Institution:Department of Physics, IBILCE/UNESP, R. Cristov?o Colombo 2265, S?o José do Rio Preto, SP, CEP 15054-000, Brazil.
Abstract:Myotoxin II, a Lys49 catalytically inactive phospholipase A(2) homologue from Atropoides nummifer venom, was purified, characterized and crystallized. The crystals belongs to the tetragonal system, space group P4(3)2(1)2, with unit cell parameters (a=b=68.66 and c=63.87 angstroms). Diffraction data were collected to a resolution of 2.32 angstroms. The crystal structure is currently being determined using molecular replacement techniques.
Keywords:
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