Demonstration of microtubules in the terminal web of mature absorptive cells from the small intestine of the rat |
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| Authors: | Susan J Hagen PhD Carol H Allan Jerry S Trier |
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| Institution: | (1) Division of Gastroenterology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, and the Harvard Digestive Disease Center, Boston, Massachusetts, USA;(2) Division of Gastroenterology, Brigham and Women's Hospital, 75 Francis Street, 02115 Boston, Massachusetts, USA |
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| Abstract: | Summary The terminal web (TW) region of mature absorptive cells in the small intestine of the rat contains an elaborate cytoskeleton which supports the apical microvillus membrane. In studies regarding the structural organization of the cytoskeleton and associated proteins in the small intestine, microtubules have not been mentioned as components of the TW. By transmission electron microscopy of conventional resin-embedded sections of rat small intestine, we observe many microtubule profiles in the TW of mature absorptive cells. These microtubules are found in various orientations, although most course parallel to the long axis of the cell, and many microtubule profiles are seen in close association with smooth-surfaced vesicles. |
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| Keywords: | Microtubules Terminal web Small intestine Electron microscopy Rat |
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