Inhibition of aldose reductase prevents endotoxin-induced inflammation by regulating the arachidonic acid pathway in murine macrophages期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Inhibition of aldose reductase prevents endotoxin-induced inflammation by regulating the arachidonic acid pathway in murine macrophages

Authors:	Shoeb Mohammad Yadav Umesh C S Srivastava Satish K Ramana Kota V

Institution:	Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA

Abstract:

Keywords:	AR aldose reductase AA arachidonic acid LPS lipopolysaccharide PGE2 prostaglandin E2 PGG2 prostaglandin G2 PGH2 prostaglandin H2 PGI2 prostaglandin I2 TXB thromboxane LTB4 leukotriene cPLA2 cytosolic phospholipase A2 sPLA2 soluble phospholipase A2 COX-2 cyclooxygenase-2 LOX-5 lipoxygenase-5 MAPK mitogen-activated protein kinase ERK extracellular signal-regulated kinase NF-κB nuclear factor-κB EGR-1 early growth response factor 1 ROS reactive oxygen species NSAID nonsteroidal anti-inflammatory drug Nrf2 nuclear factor (erythroid-derived 2)-like 2 HO-1 heme oxygenase-1 GCLC glutamate-cysteine ligase catalytic subunit GST glutathione S-transferase
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