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Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells
Authors:Mauro Gaya  Patricia Barral  Marianne Burbage  Shweta Aggarwal  Beatriz Montaner  Andrew Warren Navia  Malika Aid  Carlson Tsui  Paula Maldonado  Usha Nair  Khader Ghneim  Padraic G. Fallon  Rafick-Pierre Sekaly  Dan H. Barouch  Alex K. Shalek  Andreas Bruckbauer  Jessica Strid  Facundo D. Batista
Affiliation:1. Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA;2. The Francis Crick Institute, London NW1A 1AT, UK;3. The Peter Gorer Department of Immunobiology, King’s College London, London SE1 9RT, UK;4. Institute for Medical Engineering & Science, MIT, Cambridge, MA 02139, USA;5. Broad Institute, Cambridge, MA 02142, USA;6. Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA;7. Case Western Reserve University, Cleveland, OH 44106, USA;8. Institute of Molecular Medicine, Trinity College Dublin, Dublin, Ireland;9. Division of Immunology and Inflammation, Department of Medicine, Imperial College London, London W12 0NN, UK;10. Department of Microbiology and Immunobiology & HMS Center for Immune Imaging, Harvard Medical School, Boston, MA 02115, USA
Abstract:
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  • Keywords:NKT cells  B cells  macrophages  germinal center seeding  IL-4  viral infection  influenza  Zika virus  lymph node  CXCR3
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