Functionalization of nanostructured gold substrates with chiral chromophores for SERS applications: The case of 5‐Aza[5]helicene |
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| Authors: | Chiara Zanchi Andrea Lucotti Damiano Cancogni Francesca Fontana Sebastiano Trusso Paolo M Ossi Matteo Tommasini |
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| Institution: | 1. Dip. di Energia, Politecnico di Milano, Milan, Italy;2. Dip. di Chimica Materiali e Ing. Chimica, Politecnico di Milano, Milan, Italy;3. Dip. di Ingegneria e Scienze Applicate, Università di Bergamo, Dalmine, Italy;4. INSTM Bergamo R.U, Dalmine, Italy;5. Istituto Processi Chimico‐Fisici, CNR, Messina, Italy |
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| Abstract: | Nanostructured gold thin films can be fabricated by controlled pulsed laser deposition to get efficient sensors, with uniform morphology and optimized plasmon resonance, to be employed as plasmonic substrates in surface enhanced Raman scattering spectroscopy. By attaching 5‐aza5]helicen‐6‐yl‐6‐hexanethiol to such gold nanostructures, used in a previous work for label‐free drug sensing with biomedical purposes, we successfully prepared functionalized substrates with remarkable surface enhanced Raman scattering activity. The long‐term motivation is to develop probes for drug detection at low concentrations, where sensitivity to specific chiral targets is required. |
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| Keywords: | DFT nanostructured gold thin films plasmonic enhancement |
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