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Melav2, an elav-like gene, is essential for spermatid differentiation in the flatworm Macrostomum lignano
Authors:Kiyono Sekii  Willi Salvenmoser  Katrien De Mulder  Lukas Scharer and Peter Ladurner
Institution:(1) Department of Evolutionary Biology, Zoological Institute, University of Basel, Basel, Switzerland;(2) Department of Ultrastructural Research and Evolutionary Biology, Institute of Zoology, University of Innsbruck, Innsbruck, Austria;(3) Department of Biology, University of Ghent, Ghent, Belgium
Abstract:

Background  

Failure of sperm differentiation is one of the major causes of male sterility. During spermiogenesis, spermatids undergo a complex metamorphosis, including chromatin condensation and cell elongation. Although the resulting sperm morphology and property can vary depending on the species, these processes are fundamental in many organisms. Studying genes involved in such processes can thus provide important information for a better understanding of spermatogenesis, which might be universally applied to many other organisms.
Keywords:
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