Synthetic studies to improve the deuterium labelling in nucleosides for facilitating structural studies of large RNAs by high-field NMR spectroscopy |
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| Authors: | Kundu M K Trifonova A Dinya Z Földesi A Chattopadhyaya J |
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| Affiliation: | Department of Bioorganic Chemistry, Box 581, Biomedical Center, University of Uppsala, S-751 23 Uppsala, Sweden. |
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| Abstract: | Synthetic studies to prepare ribonucleosides deuterated at C2' and the application of the developed procedures for the synthesis of 2H5-ribonucleosides from 1,2-O-isopropylidene-3-O-benzyl-ribofuranose-3,4,5,5'-2H4 have been reported. |
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