Synthesis and base pairing properties of 9-deazapurine N7-nucleosides in oligonucleotide duplexes and triplexes |
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| Authors: | Leonard P Wiglenda T Seela F |
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| Institution: | Laboratorium für Organische und Bioorganische Chemie, Institut für Chemie, Universit?t Osnabrück, Germany. |
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| Abstract: | The 9-deazaguanine N7-2'-deoxyribofuranoside (3) as well as the bromo and iodo derivatives 4a,b were synthesized and incorporated in oligonucleotide duplexes and triplexes. Their base pairing properties were investigated and compared with those of the parent purine N7-2'-deoxyribofuanosides. |
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