Synthesis and antiviral activity of novel exomethylene cyclopropyl nucleosides |
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| Authors: | Choi B G Kwak E Y Hong J H Lee C K |
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| Institution: | Department of Medicinal Chemistry, College of Pharmacy, Chonnam National University, Kwangju 500-757, Korea. |
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| Abstract: | Novel cyclopropyl nucleosides were synthesized as potential antiviral agents. The key intermediate 5, prepared from Feist's acid 1 was condensed with purine derivatives by the SN2 type reaction. All the synthesized compounds were evaluated for antiviral activity. |
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