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Synthesis and biophysical studies of oligonucleotides containing hydroxamate linkages |
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| Authors: | Ramasamy K S Stoisavljevic V Lau J Y |
| Institution: | Medicinal Chemistry Division, ICN Pharmaceuticals, Inc., 3300 Hyland Avenue, Costa Mesa, California 92626, USA. |
| Abstract: | Novel thymidine dimers containing hydroxamate linkages were synthesized, incorporated into oligonucleotide sequences and studied their hybridization properties against complementary DNA and RNA targets. |
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