Asymmetric synthesis of carbocyclic pyrimidine nucleosides via pi-allylpalladium complex |
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Authors: | Shi J Schinazi R F |
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Affiliation: | Pharmasset, Inc., Tucker, Georgia 30084, USA. |
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Abstract: | Racemic and enantiomerically pure carbocyclic pyrimidine nucleosides were synthesized efficiently by a convergent approach using Trost nucleophilic addition of pi-allylpalladium complexes. |
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