Step-by-step control by MALDI-TOF MS of an oligonucleotide synthesis on standard CPG solid-support |
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| Authors: | Meyer A Debart F Imbach J L Vasseur J J |
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| Institution: | Lab. de Chimie Organique Biomoléculaire de Synthèse, UMR 5625 CNRS-UM2, Université Montpellier II, Place E. Bataillon, 34095, Montpellier, France. |
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| Abstract: | MALDI-TOF mass spectrometry was used to monitor DNA solid-phase synthesis on long-chain alkylamine controlled-pore glass (LCAA-CPG) with a standard succinyl linker between the solid support and the growing oligonucleotide. |
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