Cell interactions in the generation of chaetae pattern inDrosophila |
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| Authors: | J. Moscoso del Prado A. Garcia-Bellido |
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| Affiliation: | (1) Centro de Biologia Molecular, Consejo Superior de Investigaciones Cientificas, Cantoblanco, 34 Madrid, Spain;(2) Present address: Genetics Laboratory, Department of Biochemistry, University of Oxford, OX1 3QU Oxford, UK |
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| Abstract: | Summary We have already shown that theachaetae-scute complex (AS-C) ofDrosophila is regulated by two genes,hairy andextramacrochaetae. Using mutants in these genes, we have analysed how different levels of expression of AS-C affect the pattern of chaetae. The results indicate that the spatial distribution of chaetae results from cell interactions, probably by a mechanism of lateral inhibition. The results are discussed in view of the different theories of pattern formation. |
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| Keywords: | Chaetae Differentiation Genetic regulation Pattern formation Drosophila melanogaster |
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