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Increased numbers of neuroepithelial bodies (NEB) in lungs of fetal Rhesus monkeys following maternal dexamethasone treatment |
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| Authors: | Dr. A. M. Dayer Y. Kapanci A. Rademakers L. M. Rusy J. De Mey J. A. Will |
| Affiliation: | (1) Departments of Veterinary Science, CALS, Anesthesiology, Medical School, University of Wisconsin, Madison, Wisconsin, USA;(2) Departments of Anesthesiology, Medical School, University of Wisconsin, Madison, Wisconsin, USA;(3) Department of Pathology, University Hospital, Geneva, Switzerland;(4) Janssen Pharmaceutica, Beerse, Belgium;(5) Dept. of Veterinary Science, University of Wisconsin, 1655 Linden Drive, 53706 Madison, WI, USA |
| Abstract: | Summary Numbers of neuroepithelial bodies in the lungs of fetal Rhesus monkeys increase in a dose-dependent manner when mothers are treated antenatally with dexamethasone. Maternal doses of 15 mg/kg result in numbers of neuroepithelial bodies in lungs of fetuses of 135-day gestational age not different from those of the mature control group at 162 days. Controls at 135 days are significantly different from those at 162 days. Serotonin immunoreactive neuroepithelial bodies were localized by immunocytochemistry. |
| Keywords: | Lung Dexamethasone Neuroepithelial bodies Serotonin Macaca mulatta |
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