A two-layered mechanical model of the rat esophagus. Experiment and theory |
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| Authors: | Fan Yanhua Gregersen Hans Kassab Ghassan S |
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| Affiliation: | (1) Institute of Experimental Clinical Research, Skejby Hospital, Aarhus, Denmark;(2) Center for Biomechanics and Visceral Pain, Aalborg Hospital, Aalborg, Denmark;(3) Center for Sensory-Motor Interaction, Aalborg University, Aalborg, Denmark;(4) Haukeland University Hospital, Bergen, Norway;(5) Department of Biomedical Engineering, UC Irvine, Irvine, California |
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| Abstract: | Background The function of esophagus is to move food by peristaltic motion which is the result of the interaction of the tissue forces in the esophageal wall and the hydrodynamic forces in the food bolus. The structure of the esophagus is layered. In this paper, the esophagus is treated as a two-layered structure consisting of an inner collagen-rich submucosa layer and an outer muscle layer. We developed a model and experimental setup for determination of elastic moduli in the two layers in circumferential direction and related the measured elastic modulus of the intact esophagus to the elastic modulus computed from the elastic moduli of the two layers. |
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