(1) Department of Genetics, Stanford University, Stanford, CA 94305-9010, USA;(2) Department of Pathology, Stanford University, Stanford, CA 94305-5324, USA
Abstract:
Background
Alignment and comparison of related genome sequences is a powerful method to identify regions likely to contain functional elements. Such analyses are data intensive, requiring the inclusion of genomic multiple sequence alignments, sequence annotations, and scores describing regional attributes of columns in the alignment. Visualization and browsing of results can be difficult, and there are currently limited software options for performing this task.