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HLA antigen,gene, and haplotype frequencies in Thailand
Authors:J. Greiner  E. Schleiermacher  V. Lenhard  P. Kulapongs  F. Vogel
Affiliation:(1) Institut für Anthropologie und Humangenetik der Universität Heidelberg, Im Neuenheimer Feld 328, D-6900 Heidelberg, Federal Republic of Germany;(2) Institut für Anthropologie der Universität Mainz, Saarstraße 21, D-6500 Mainz, Federal Republic of Germany;(3) Institut für Immunologie und Serologie der Universität Heidelberg, Im Neuenheimer Feld 305, D-6900 Heidelberg, Federal Republic of Germany;(4) Department of pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Abstract:Summary Antigen, gene, and haplotype frequencies as well as phenotype distribution of the HLA system were studied in a series of 213 individuals in northern Thailand. The series consisted of 160 northern Thais, 23 Thai individuals from various other regions of Thailand, and 25 persons of Chinese origin. Most frequently found were the alleles HLA-A11 and HLA-Bw40 and the haplotype HLA-A2, B-. Phenotype distribution followed a Hardy-Weinberg expectation. Significant differences were found especially between our results for the alleles of locus B and the results of a series from Bangkok reported by Chiewsilp and Chanarat (1976).
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