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Landomycin A inhibits DNA synthesis and G1/S cell cycle progression. |
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| Authors: | R T Crow B Rosenbaum R Smith Y Guo K S Ramos G A Sulikowski |
| Affiliation: | Department of Chemistry, Texas A&M University, College Station 77842, USA. |
| Abstract: | Landomycin A was found to inhibit the uptake of [3H]thymidine into DNA in murine smooth muscle cells indicating decreased DNA synthesis. Subsequent studies showed that landomycin A inhibits cell cycle progression. |
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