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Reconstruction of molecular phylogeny of extant hominoids from DNA sequence data
Authors:N Saitou
Institution:Department of Anthropology, Faculty of Science, University of Tokyo, Japan.
Abstract:Evolutionary distance matrices of the extant hominoids are computed from DNA sequence data, and hominoid DNA phylogenies are reconstructed by applying the neighbor-joining method to these distance matrices. The chimpanzee is clustered with the human in most of the phylogenetic trees thus obtained. The proportion of the distance between human and chimpanzee to that between human/chimpanzee and orangutan is estimated. Both mitochondrial DNA and nuclear DNA show a similar value (0.44), which is close to values derived from DNA-DNA hybridization data.
Keywords:Human-chimpanzee-gorilla triad  Nucleotide substitutions  Neighbor-joining method
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