High-throughput identification of interacting protein-protein binding sites |
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Authors: | Jo-Lan Chung Wei Wang Philip E Bourne |
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Institution: | (1) Department of Chemistry and Biochemistry, University of California, San Diego, Gilman Drive, La Jolla, CA 92093-0743, USA;(2) Department of Pharmacology, University of California, San Diego, Gilman Drive, La Jolla, CA 92093-0743, USA;(3) San Diego Supercomputer Center, University of California, San Diego, Gilman Drive, La Jolla, CA, 92093-0743 USA |
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Abstract: | Background With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein
binding sites from protein surfaces. Therefore, methods that are able to identify whether these binding sites interact are
needed. |
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Keywords: | |
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