Small leucine-rich proteoglycans in the aging skeleton |
| |
| Authors: | Young M F Bi Y Ameye L Xu T Wadhwa S Heegaard A Kilts T Chen X D |
| |
| Affiliation: | Craniofacial and Skeletal Diseases Branch, NIDCR, NIH, Bethesda, MD 20892, USA. myoung@dir.nidcr.nih.gov |
| |
| Abstract: | Small Leucine-Rich Proteoglyans (SLRPs) are major skeletal extracellular matrix (ECM) components that comprise a family of 13 members containing repeats of a leucine-rich motif. To examine SLRP function, we generated mice deficient in one or more member and analyzed them at the tissue, cell and molecular levels. This review outlines the novel research findings uncovered using these new animal models. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
