ABCG4: a novel human white family ABC-transporter expressed in the brain and eye |
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| Authors: | Oldfield Susan Lowry Christopher Ruddick Jon Lightman Stafford |
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| Institution: | University Research Centre for Neuroendocrinology, BRI, University of Bristol, Marlborough Street, Bristol BS2 8HW, UK. s.oldfield@bristol.ac.uk |
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| Abstract: | White family transporters are a group of ATP-binding cassette (ABC) proteins that show sequence homology to the Drosophila white gene product. The Drosophila protein is a subunit of heterodimeric transporters of precursors for eye-pigment synthesis. A novel, human member of this family (ABCG4) has been identified. Northern blotting shows that ABCG4 is expressed specifically in the brain and the eye. |
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