A Case of Adrenal Cavernous Hemangioma Presenting with Progressive Enlargement and Apparent Hormonal Hypersecretion |
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| Institution: | 1. Department of Endocrinology, Singapore General Hospital, Singapore.;2. Department of Pathology, Singapore General Hospital, Singapore.;3. Department of Urology, Singapore General Hospital, Singapore.;1. Section of Pathologic Anatomy, University Hospital Policlinico of Modena, Modena;;2. Department of Oncology and Advanced Technologies, Operative Unit of Oncology, Arcispedale S. Maria Nuova/I.R.C.C.S., Reggio Emilia;;3. Department of Oncology, University Hospital Policlinico of Modena, Modena;;4. Division of Medical Oncology University Hospital, Parma, Italy;1. JC School of Public Health and Primary Care; Faculty of Medicine, The Chinese University of Hong Kong;2. Office of Global Engagement; Faculty of Medicine, The Chinese University of Hong Kong;3. Department of Surgery; Faculty of Medicine, The Chinese University of Hong Kong;4. Department of Medicine and Therapeutics; Faculty of Medicine, The Chinese University of Hong Kong.;1. Department of Surgery, University of Wisconsin, Madison, WI;2. Department of Pathology, MetroHealth Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH;3. Department of, Radiology, MetroHealth Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH;4. Department of Surgery, MetroHealth Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH;5. Department of MetroHealth Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH |
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| Abstract: | ObjectiveTo report the case of a man with an adrenal cavernous hemangioma presenting as a progressively enlarging adrenal mass with apparent hormonal hyper-secretion.MethodsWe report the clinical, laboratory, imaging findings, and clinical course of this patient, and we highlight the important atypical features of this case. The literature is reviewed for the typical presentations of adrenal cavernous hemangiomas.ResultsA 59-year-old man presented with an adrenal incidentaloma that had an imaging phenotype suggestive of a pheochromocytoma or an adrenal carcinoma. The hormonal profile also suggested a state of aldosterone and catecholamine hypersecretion. Surgery, however, proved the diagnosis to be an adrenal cavernous hemangioma.ConclusionAlthough adrenal cavernous hemangioma is a rare entity, it should be considered in the differential diagnosis of an adrenal incidentaloma. Its radiologic features are not specific, and the presence of hormonal hypersecretion does not exclude the diagnosis. (Endocr Pract. 2008;14:104-108) |
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