Evidence of oxygen limitation in a hollow fibre reactor with immobilized E. coli |
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| Authors: | S. L. Paterson A. G. Fane C. J. D. Fell P. L. R. Rogers |
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| Affiliation: | (1) School of Chemical Engineering and Industrial Chemistry and School of Biotechnology, University of New South Wales, P O Box 1, 2033 Kensington, NSW, Australia |
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| Abstract: | Summary A hollow fibre reactor (HFR) has been used to immobilize a regulatory mutant ofE. coli to produce phenylalanine. Fermentation performance in the HFR using both air and pure oxygen shows evidence of significant oxygen limitation. In particular, levels of volatile fatty acids (VFA) produced served as an indication of oxygen limitation. |
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